Introduction
These Creamy Chicken, Spinach and Mushroom Lasagna Roll-Ups are the ultimate comfort-food dinner, combining tender shredded chicken, earthy mushrooms, creamy cheese, and spinach inside delicate lasagna sheets.
The rolls are covered with a rich, creamy white sauce and plenty of melted mozzarella, then baked until bubbling and beautifully golden on top.
This cozy baked pasta dish is perfect for family dinners, Sunday meals, holidays, or whenever you’re craving a hearty homemade casserole with plenty of cheesy goodness.
Recipe Overview
| Details | Information |
| Prep Time | 30 minutes |
| Cook Time | 35 minutes |
| Total Time | 1 hour 5 minutes |
| Yield | 8 servings |
| Difficulty | Moderate |
| Oven Temperature | 375°F (190°C) |
| Dish Size | 9 × 13-inch |
🍗 Ingredients
For the Chicken Filling
| Ingredient | Amount |
| Cooked chicken, shredded | 3 cups (about 450 g) |
| Fresh spinach | 3 cups |
| Mushrooms, finely sliced | 8 oz (225 g) |
| Yellow onion, finely diced | 1 small |
| Garlic, minced | 3 cloves |
| Olive oil | 1 tablespoon |
| Ricotta cheese | 1 cup |
| Cream cheese, softened | 4 oz (115 g) |
| Grated Parmesan cheese | ½ cup |
| Italian seasoning | 1 teaspoon |
| Salt | ½ teaspoon |
| Black pepper | ½ teaspoon |
For the Pasta
| Ingredient | Amount |
| Lasagna noodles | 12 |
| Water | For boiling |
| Salt | For pasta water |
For the Creamy White Sauce
| Ingredient | Amount |
| Butter | 4 tablespoons |
| All-purpose flour | 4 tablespoons |
| Milk | 2 cups |
| Heavy cream | 1 cup |
| Garlic powder | ½ teaspoon |
| Parmesan cheese | ½ cup |
| Salt | ½ teaspoon |
| Black pepper | ¼ teaspoon |
| Nutmeg | Small pinch, optional |
For the Topping
| Ingredient | Amount |
| Shredded mozzarella cheese | 2 cups |
| Parmesan cheese | ¼ cup |
| Fresh parsley or basil | For garnish |
🍝 Step-by-Step Instructions
Cook the Lasagna Noodles
Bring a large pot of salted water to a boil.
Cook the lasagna noodles according to the package directions until they are al dente.
Avoid overcooking them because they will continue cooking in the oven.
Drain the noodles carefully and arrange them flat on a lightly oiled baking sheet or parchment paper so they don’t stick together.
Prepare the Chicken
If you’re using freshly cooked chicken, allow it to cool slightly before shredding.
You can use roasted chicken, poached chicken, or leftover cooked chicken.
Shred the chicken into small pieces so it will be easy to spread across the lasagna noodles.
Set aside.
🍄 Cook the Mushrooms and Spinach
Heat the olive oil in a large skillet over medium heat.
Add the diced onion and sliced mushrooms.
Cook for approximately 5–7 minutes, stirring occasionally, until the mushrooms become tender and lightly browned.
Add the minced garlic and cook for another 30–60 seconds.
Add the fresh spinach.
Cook for approximately 2–3 minutes, stirring frequently, until the spinach wilts.
Remove the skillet from the heat.
Allow the mixture to cool slightly.
🧀 Make the Creamy Chicken Filling
Place the shredded chicken in a large bowl.
Add the cooked mushroom and spinach mixture.
Stir in the ricotta, softened cream cheese, Parmesan, Italian seasoning, salt, and black pepper.
Mix until the ingredients are evenly combined.
The filling should be creamy but thick enough to spread easily over the lasagna noodles.
Taste and adjust the seasoning if necessary.
🥛 Prepare the Creamy White Sauce
Melt the butter in a medium saucepan over medium heat.
Sprinkle in the flour and whisk continuously for approximately 1–2 minutes.
Slowly pour in the milk while whisking constantly to prevent lumps.
Add the heavy cream.
Continue cooking for approximately 4–6 minutes, stirring frequently, until the sauce becomes smooth and thick enough to coat the back of a spoon.
Add the garlic powder, Parmesan, salt, black pepper, and optional pinch of nutmeg.
Stir until the Parmesan has melted completely.
Remove from the heat.
If the sauce becomes too thick, whisk in a small splash of milk.
🧀 Assemble the Lasagna Roll-Ups
Preheat your oven to 375°F (190°C).
Spread approximately 1 cup of the creamy white sauce across the bottom of a 9 × 13-inch baking dish.
Take one cooked lasagna noodle and lay it flat.
Spread approximately ⅓ cup of the chicken filling evenly over the noodle.
Do not spread the filling all the way to the very edges.
Starting from one short end, carefully roll the noodle into a compact cylinder.
Place the roll seam-side down in the prepared baking dish.
Repeat with the remaining noodles and filling.
Arrange the rolls snugly beside one another.
🥛 Add the Sauce
Pour the remaining creamy white sauce evenly over the lasagna rolls.
Use a spatula to spread the sauce across the entire surface.
Make sure the edges of the noodles are coated because exposed pasta can become dry during baking.
🧀 Add the Cheese
Sprinkle the shredded mozzarella evenly over the top.
Add the Parmesan cheese.
For the beautiful golden finish seen in the image, make sure the cheese is distributed evenly across the entire casserole.
🔥 Bake
Cover the baking dish loosely with aluminum foil.
Bake for approximately 20 minutes.
Remove the foil and continue baking for another 12–15 minutes, until the cheese is melted, bubbling, and golden brown.
For an extra golden top, place the casserole under the broiler for 1–2 minutes, watching carefully so the cheese doesn’t burn.
🌿 Rest and Garnish
Remove the lasagna roll-ups from the oven.
Let them rest for approximately 10 minutes before serving.
This gives the creamy filling time to settle and makes the rolls easier to lift from the dish.
Garnish with freshly chopped parsley or basil.
Serve warm.
💡 Best Tips
Don’t overcook the noodles. Al dente noodles are much easier to roll and won’t become mushy during baking.
Don’t make the filling too wet. Cook the mushrooms and spinach thoroughly so excess moisture evaporates before combining them with the cheeses.
Use softened cream cheese. Softened cream cheese blends much more easily with the ricotta and chicken.
Don’t overfill the noodles. Too much filling makes the rolls difficult to close and can cause them to unravel during baking.
Cover the casserole initially. Foil helps keep the pasta moist while the filling heats through.
Remove the foil for the final bake. This allows the mozzarella to brown beautifully.
Let the dish rest. Ten minutes makes a noticeable difference when serving.
🥬 Best Ingredient Options
Chicken
Cooked rotisserie chicken is an excellent shortcut. You can also use leftover roasted chicken or poached chicken.
Mushrooms
Cremini mushrooms provide excellent flavor, but white button mushrooms or a mixture of mushrooms can also be used.
Spinach
Fresh spinach works beautifully, but frozen spinach can also be used. If using frozen spinach, thaw it completely and squeeze out as much water as possible.
Cheese
Ricotta creates a classic creamy filling, while cream cheese adds extra richness.
Mozzarella provides the stretchy, golden topping, and Parmesan contributes a savory flavor.
Pasta
Traditional lasagna noodles work best because they’re large enough to roll around the filling.
🔄 Recipe Variations
Chicken Alfredo Lasagna Roll-Ups
Increase the amount of Parmesan in the white sauce and add extra garlic for a richer Alfredo-inspired flavor.
Spinach and Mushroom Roll-Ups
Leave out the chicken and increase the mushrooms and spinach for a satisfying vegetarian variation.
Broccoli Chicken Roll-Ups
Replace some of the spinach with finely chopped cooked broccoli.
Three-Cheese Chicken Roll-Ups
Add shredded mozzarella directly to the chicken filling along with the ricotta and Parmesan.
Sun-Dried Tomato Chicken Roll-Ups
Finely chop sun-dried tomatoes and mix them into the chicken filling for a sweet, tangy flavor.
Spicy Chicken Roll-Ups
Add crushed red pepper flakes or a pinch of cayenne to the creamy sauce for a little heat.
🥗 What to Serve With
A crisp green salad is a perfect accompaniment to these rich and creamy lasagna roll-ups.
Garlic bread is another classic choice and is excellent for soaking up the creamy white sauce.
Roasted broccoli, asparagus, or green beans also make wonderful vegetable sides.
For a lighter dinner, serve the roll-ups with a simple salad dressed with lemon and olive oil.
⏰ Make-Ahead Instructions
These lasagna roll-ups are excellent for meal preparation.
Prepare the filling and assemble the entire casserole up to 24 hours in advance.
Cover tightly and refrigerate.
When ready to bake, remove the casserole from the refrigerator while the oven preheats.
Because the dish starts cold, you may need to add approximately 5–10 minutes to the covered baking time.
🧊 Storage
Allow leftovers to cool before transferring them to airtight containers.
Refrigerate for up to 3–4 days.
Individual portions are convenient for quick lunches or weeknight dinners.
🔥 Reheating
For the best results, place individual portions in an oven-safe dish.
Cover loosely with foil and reheat at 350°F (175°C) for approximately 15–20 minutes.
You can also microwave individual portions for approximately 2–3 minutes, depending on your microwave.
Add a small spoonful of milk or cream to the dish if the sauce has thickened during refrigeration.
❄️ Freezing
These lasagna roll-ups can be frozen either before or after baking.
For an unbaked casserole, assemble the rolls and cover the dish tightly with plastic wrap followed by aluminum foil.
Freeze for up to 2–3 months.
Thaw overnight in the refrigerator before baking.
For baked leftovers, allow the casserole to cool completely before freezing individual portions in freezer-safe containers.
⚠️ Common Mistakes to Avoid
Overcooking the noodles: Very soft noodles can tear when rolled.
Leaving excess water in the mushrooms: Mushrooms release a lot of moisture, so cook them until the pan is relatively dry.
Using watery spinach: Excess water can make the filling loose and affect the final texture.
Overfilling the rolls: A moderate layer of filling makes them easier to roll and serve.
Using cold cream cheese: Cold cream cheese can create lumps in the filling.
Making the white sauce too thick: The sauce should be creamy and pourable because it continues thickening in the oven.
Skipping the resting time: Allowing the casserole to rest makes the rolls much easier to serve neatly.
🍽️ Nutrition Estimate
Approximate values per serving, based on 8 servings. Actual nutrition will vary according to the ingredients and brands used.
| Nutrient | Estimated Amount |
| Calories | 620 kcal |
| Protein | 39 g |
| Carbohydrates | 44 g |
| Fat | 34 g |
| Saturated Fat | 18 g |
| Fiber | 3 g |
| Sugar | 6 g |
| Sodium | 820 mg |
❓ Frequently Asked Questions
Can I use rotisserie chicken?
Yes. Rotisserie chicken is one of the easiest options for this recipe. Remove the skin and bones, then shred the meat before adding it to the filling.
Can I use frozen spinach?
Yes. Thaw the spinach completely and squeeze it very well to remove excess water before adding it to the filling.
Can I use jarred Alfredo sauce?
Yes. If you’re short on time, a good-quality Alfredo sauce can replace the homemade white sauce.
Can I prepare the roll-ups the night before?
Absolutely. Assemble the entire casserole, cover it tightly, and refrigerate overnight. Bake the following day.
Why are my lasagna rolls watery?
Excess moisture usually comes from the mushrooms or spinach. Cook fresh mushrooms until their liquid has evaporated, and squeeze frozen spinach thoroughly after thawing.
Can I add more cheese?
Yes. Extra mozzarella can be added to the top for an even cheesier casserole.
How do I keep the lasagna noodles from sticking together?
After draining, lay the cooked noodles flat on a lightly oiled baking sheet or parchment paper instead of stacking them.
Can I make this recipe without chicken?
Yes. Simply increase the mushrooms and spinach, or substitute the chicken with cooked vegetables for a vegetarian version.
🌟 Final Thoughts
These Creamy Chicken, Spinach and Mushroom Lasagna Roll-Ups turn classic lasagna ingredients into a beautiful, easy-to-serve baked pasta casserole.
Each roll is filled with tender chicken, savory mushrooms, spinach, ricotta, cream cheese, and Parmesan, then covered in a silky homemade white sauce and a generous layer of golden mozzarella.
The combination of creamy filling, tender pasta, and bubbling cheese makes this a perfect comfort food dinner for family meals, weekend gatherings, and special occasions.
For the best result, keep the pasta al dente, remove excess moisture from the vegetables, avoid overfilling the noodles, and let the casserole rest for a few minutes before serving.